Re: BMJ 2005;331:1515-1518 (24 December)
I suggest there is a treatment for hangover that has been overlooked.
Alcohol increases cortisol and DHEAS. DHEAS is the precursor of DHEA. If
DHEAS is increased, then DHEA, the active molecule, is decreased. It is
known that cortisol exerts negative effects on all systems, especially the
nervous system and the opposite is found for DHEA. So, alcohol
exaggerates
the cortisol to DHEA ratio. I suggest the treatment for hangover is DHEA.
However, according to a search of the medical literature, this has not
been
examined.
From a personal point of view, when I have taken DHEA prior to alcohol
use,
I do not experience the effects normally produced by alcohol.
James Michael Howard
Fayetteville, Arkansas, U.S.A.
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